A substance for suppressing the action of genes

Listning ID 148501


Farmers can use these genes off substances to accelerate growth, enhance the nutritional value of plants, to protect them from insects and viruses. This technique gives the ability to change the characteristics of plants, without keeping their DNA unchanged.

"Substance can be used directly, no need to wait for years until DNA modify or withdraw a new variety," says David Balcomb from Cambridge, who studies the technology of gene silencing in plants. Thus one material can be used in different types and varieties.

And the company like "Monsanto Company", are already developing similar substances, which penetrate into insects and kill them by disabling certain vital genes.

Scientists from the University of Queensland in Australia was able to achieve prolonged effect of turning off genes inside plant cells. They protected tobacco plants from the action of the virus for 20 days with only one application turn off genes matter. This technique allows you to change various characteristics in plants, but scientists have not yet conducted such experiments, focusing on the technology of crop protection.

Deactivation of genes uses a system of natural protection. When the viruses infect the cells, the cells cut out part of the RNA to produce small samples of double stranded RNA, which are used to recognize and destroy any RNA that matches the pattern. No viral RNA, no viral proteins, and therefore, viruses can't reproduce.

RNA interference can be used to block any protein. Attempts to develop drugs based on this technology for people while not successful, as when injected into the blood RNA disintegrate rapidly. And in plants it works like this:

  • positively charged clay nanoparticles made from chloride of magnesium, for example, bind and protect negatively charged RNA.

  • over time, particles interact with carbon dioxide and disintegrate slowly releasing RNA.

Plant viruses are a problem for agriculture around the world and in Ukraine, and none of the currently existing funds are not sent directly to them. Of course farmers can grow virus-resistant varieties, if such exist, or kill organisms-vectors, like aphids. So, if an antivirus product will show themselves well in the field, it will be extremely popular.

However, there is a big problem — the cost.

Clay nanoparticles are cheap, but the production of RNA is expensive. A couple of years ago one gram of this substance, which would be enough for a small field, it was worth $ 100,000. But that quickly changed. For example, Apse aims to mass-produce RNA for only $ 2 per gram.

The stuff that turns the genes will be safer than ordinary pesticides. RNA cannot penetrate human skin and are quickly degraded in the body.

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